best ergonomic gaming mice

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Finding the best gaming mouse for you can be a complicated and tedious process. Finding an ergo mouse that’s comfortable can be even more complicated. That’s why we searched, reviewed, and compiled a list of the best ergonomic gaming mouse for gaming so you don’t have to.

Best Ergonomic Gaming Mouse

Logitech MX Master 3S | $99.99

Our best ergonomic gaming mouse is the legendary Logitech MX Master 3S. This bad boy was built with comfort in mind from the very start. Although this mouse is slightly on the larger side, this mouse was designed for top-notch grip and control during intense play sessions.

Based on all of the factors we used to decide which mice were best, the Logitech MX Master 3S took the spotlight. From the high-quality scroll wheel to the accessible verticle one, this mouse covers all of the bases.

Pros and Cons

  • Top-Tier Ergonomics

  • Whisper-Quiet Clicks

  • Highly Customizable

  • Slightly Pricey

  • Heavy

  • Software Bloat

Best Budget Ergonomic Gaming Mouse

Logitech M720 | $34.99

When deciding the best budget ergonomic gaming mouse, we had to consider more than just the price. We also accounted for build quality, longevity, and price to find the ultimate best bang for your buck.


That’s why the Logitech M720 Triathlon takes the cake when it comes to affordability and is considered one of the best budget gaming mice.


Keeping a rather simplistic design, the contours of the M720 still make sure it’s ergonomic by design while not shelling out for some of the more luxurious offerings of the other comfortable gaming mice. 


We recommend the M720 if you’re looking for a new mouse when first learning how to build a gaming PC.

Pros and Cons

  • Budget-Friendly

  • Reliable Sensor

  • Multi-Device Connectivity

  • Limited Buttons

  • No Hyper-Scrolling

  • Not Ideal For Large Hands

Best Wireless Ergonomic Gaming Mouse

Razer Viper V2 Pro | $149.99

Modern gaming mice have no issues with wireless adapters. It’s super easy to use the Razer Viper V2 Pro without the hassle of a cord following you around. 


That’s why we voted the Viper V2 Pro as the best wireless ergonomic gaming mouse. The V2 Pro is much lighter than its predecessors but still has extreme precision and is considered one the best wireless gaming mice.


This wireless mouse is ideal for gamers who prefer claw or fingertip grip. The versatility and ultra-low latency make the V2 Pro an excellent choice when looking for an elite wireless mouse.

Pros and Cons

  • Wireless

  • Lightweight

  • High-Quality Optical Sensor

  • Limited Button Configuration

  • No On-Board Memory

  • Expensive

Best Vertical Gaming Mouse

Logitech MX Vertical | $89.99

The Logitech MX Vertical is a perfect choice for gamers looking to reduce wrist strain as much as possible. Vertical gaming mice are designed to reduce strain while still providing excellent precision with day-to-day tasks and productivity. 


The MX Vertical is one of the best ergonomic gaming mice out there due to its legendary vertical design.


The fast charging capabilities of the MX Vertical and easy multi-device support make it an ideal vertical mouse for gamers who use more than one PC (looking at you, remote workers!)

Pros and Cons

  • Vertical Design

  • Smooth Scrolling

  • Multi-Device Support

  • Limited Button Configuration

  • No On-Board Memory

  • Expensive

Best Ergonomic Gaming Mouse For Big Hands

Razer DeathAdder V2 | $69.99

The Razer DeathAdder 2 is designed for people who have big hands. This beast of a mouse features a 20K optical sensor, cutting-edge 400 IPS tracking, and has as many programmable buttons as you could ever need on an ergonomic gaming mouse.


The DeathAdder V2 improves upon the earlier model of the DeathAdder in virtually every way. Not only is the large size of the mouse perfect for large hands, but the lightweight design also keeps it easy to move around when gaming. 


We hope you enjoyed our list of the best ergonomic gaming mouse for 2023. If you’re building your first rig, check out our guide on the best prebuilt gaming PCs.

Pros and Cons

  • Large Size

  • Killer Precision

  • Super Durable

  • Limited Button Configuration

  • No On-Board Memory

  • Mid-priced

Ergonomic Mice FAQ

What Is An Ergonomic Mouse?

An ergonomic mouse is a type of computer mouse designed to improve comfort and reduce the risk of musculoskeletal disorders (MSDs) like carpal tunnel syndrome, repetitive strain injury (RSI), and tendinitis.

Are Ergonomic Mice Still Good?

Absolutely! Ergonomic gaming mice can do just about anything regular mice can with the additional benefit of a ergonomic design.

Should I Buy An Ergonomic Mouse?

It depends on personal preference. For the most part, using an ergonomic mouse will have minimal downsides to precision and performance but will decrease the risk of carpal tunnel syndrome.

By Derek

Derek, a 28-year-old residing in Chicago, IL, is an avid video game enthusiast who has been immersed in the gaming world since his childhood. From the moment he laid hands on his first console, Derek's passion for video games ignited and has continued to burn brightly throughout his life.

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